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分类:网游动漫 最新章节:重生女儿家小说国

作者:泊客阿飞
更新:2021-03-03 20:36:07

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癌症——人类生命延长的标志——兼浅谈癌症的治疗和预防Cancer-thehallmarkoftheprolongationofhumanlife-talksaboutthetreatmentandprophylaxisofcancer.摘要:用端粒酶理论来解释癌症的发生原因,指出预知癌症发生的一般标准。告知中医治疗癌症的机理——活血化瘀,提出癌症的治疗和预防的基本设想。Absrtact:telomerasetheoryisusedtoexplainthecauseofcancerandtopointoutthegeneralcriteriaforpredictingtheoccurrenceofcancer.ToinformTCMofthemechanismoftreatingcancer-promotingbloodcirculationandremovingbloodstasis,andputtingforwardthebasicideaofcancertreatmentandprevention声明:本文只是个人观点,并不代表当今的科学,只是用来和有关人士交流,不希望有人按照本文的说法来实践。declare:thisarticleisapersonalviewanddoesnotrepresenttoday'sscience.Onlyusedtocommunicatewithrelevantpeople,donotwanttobeasdescribedinthisarticletopractice.如果有人按照本文的说法去行动,后果自负。Ifanyoneactsaccordingtothisarticle,theconsequenceswillbeborne.这是这我上科学课的课题。Thisisthesubjectofmyscienceclass.人们谈癌色变,对患癌症极其恐惧。Peopletalkaboutcancerandfearcancer.学生们听到我要讲癌症这个问题时,觉得有点奇怪却有很大的期待。WhenthestudentsheardthatIwasgoingtotalkaboutcancer,theyfeltalittlestrangebuthadgreatexpectations.当我把《癌症——人类生命延长的标志》写在黑板上时,他们面面相觑,很惊讶,个个目不转睛全神贯注地盯着我看,眼神里流露出异样又疑惑的神情。WhenIwroteCancer-asignofprolongationofHumanLifeontheblackboard,theylookedateachother,astonished,andstaredintentlyatme,withastrangeandconfusedlookintheireyes.我主要谈了几点理由:1、人们对三百具木乃伊(大致3000年前)检测癌症时,只发现一具。而对85岁以上(非癌症死亡)的现代人检测中,发现这些人几乎都有癌细胞或癌症。I'mgoingtotalkaboutacoupleofreasons:1、Onlyonewasfoundwhenthreehundredmummiesweredetectedcancer(about3000yearsago),andinmodernpeopleover85yearsofage(noncancerdeaths),theyfoundalmostallcancercellsorcancer.这说明伴随着人类寿命的延长,癌症必然多发。Thisshowsthatwiththeprolongationofhumanlife,cancerisboundtooccur.反过来也可以说,癌症多了意味着是人类生命延长给癌症带来的“好处”。Conversely,morecancermeansthattheprolongationofhumanlifeisthe"benefit"ofcancer.2、上海是全国寿命最长的城市,最近几年的调查发现,上海的癌症发病率和死亡率也是全国最高的(之一)2.Shanghaiisthecitywiththelongestlifeexpectancyinthecountry.Inrecentyears,asurveyhasfoundthattheincidenceandmortalityofcancerinShanghaiisalsothehighestinthecountry.3、人类寿命为什么会延长呢?是因为人类吃的比先前更好了,人的身体的各种细胞的端粒酶更活跃了。3.Whydopeoplelivelonger?Becausehumanseatbetterthanbefore,thehumanbody'svariouscellsaremoreactiveintelomerase从端粒酶的角度来讲,端粒酶活跃的人群身体强壮,寿命自然长一点,但同时也使得癌细胞的端粒酶也活跃,个别人得癌症的概率就大。Fromthetelomerasepointofview,telomeraseactivepeoplearestronger,longerlifenaturally,butalsomaketelomeraseofcancercellsactive,individualshaveahighprobabilityofcancer.两者比较来看,益处大于损处。Incomparison,thebenefitsaregreaterthanthedamage.但是我们要注意并认识到,人类和个别人是有区别的。ButweshouldpayattentiontoandrealizethatHumansandindividualsaredifferent.得癌症的个别人寿命自然短。Individualswithcancernaturallyliveshortlives.可见,人类细胞端粒酶活跃了,平均寿命就长了,而端粒酶的活跃又是得癌症的一个标志。Wecanseethatthetelomeraseactivityinhumancellsisactive,andtheaveragelifespanislonger,andtheactivityoftelomeraseisamarkerofcancer.所以也可以认为癌症的多少可反映人类的寿命长短。Soitcanalsobeassumedthatthenumberofcancerscanreflectthelengthofhumanlife.这里的逻辑是,癌症多了说明了端粒酶更活跃了,而端粒酶活跃了,非癌细胞活性更强,人类寿命就更长。Thelogichereisthatmorecancermeansthattelomeraseismoreactive,thatnon-cancercellsaremoreactive,andthatpeoplelivelonger.所以,癌症是人类生命延长的标志。Therefore,cancerisasignofprolongationofhumanlife.我们认为,过去人的寿命短,原因是非癌细胞的端粒酶不活跃,不能有效地抵御外界或细菌或病毒的侵犯,也就是所谓的人身自身的抵抗力比较弱。Webelievethatinthepastpeoplelivedashortlifebecausethetelomeraseofnon-cancercellswasnotactiveandcouldnoteffectivelyresisttheinvasionoftheoutsideorbacteriaorviruses,thatis,theso-calledbody'sownresistanceisrelativelyweak.现在不一样了,端粒酶普遍活跃了,这是人类寿命得以延长的主体(或主因),而医疗水平的提高是人类寿命延长的次因。Now,telomeraseactivityiswidespread,whichisthemainreasonfortheincreaseinhumanlifespan,andtheincreaseinmedicalstandardsisthesecondarycauseoftheincreaseinhumanlifespan.所以从逻辑上推理有了这个结论:身体强壮是和端粒酶完全相关的。Sothelogicalconclusionisthatstrongbodyiscloselyrelatedtotelomerase.但强壮的人容易的癌症,也是因为和端粒酶有关,这没有矛盾。Butstrongpeoplearepronetocancer,alsobecausetelomeraseisinvolved,whichisnocontradiction.以上分析告诉我们,如果端粒酶是用来修复端粒的,而细胞端粒少损坏,细胞寿命就长是正确的话,那么端粒酶活性强是否就一定能延长个人的寿命?Theaboveanalysistellsusthatiftelomeraseisusedtorepairtelomeresanditisrightforcellstolivelongerwithlessdamagetotelomeres,doesthestrongactivityoftelomerasenecessarilyprolongthelifespanofindividuals?并不完全是。Notexactly.癌细胞有最典型的“好的”端粒,得了癌症的人寿命就较短了。Cancercellshavethemosttypical"good"telomeres,andpeoplewithcancerliveshorterlives.我是物理和数学方面的学者,懂了数理方面的统计。Iamascholarinphysicsandmathematicsandunderstandstatisticsinmathematics.由于癌细胞的参与,并不是端粒酶越活跃人体的寿命就越长。Becauseoftheinvolvementofcancercells,itisnotthetelomerasethatismoreactivethelongerthebodylives.作出人体寿命和端粒酶活跃的曲线,会有一个峰值(这里不显示)。Tomakeacurveofhumanlifeandtelomeraseactivity,therewillbeapeak(notshownhere).在过去人的寿命短,是端粒酶不活跃的结果。Inthepast,lifeexpectancywasshort,asaresultofinactivityoftelomerase.那时端粒酶越活跃,寿命就延长。Themoreactivethetelomerase,thelongerthelifespan.而现在的人端粒酶已够活跃,再提高端粒酶活性可能对某些人并不是好的事情。Nowthattelomeraseisactiveenough,raisingtelomeraseactivitymaynotbeagoodthingforsomepeople.由此我们进一步认为,如果端粒酶能修复染色体因分裂而损伤端粒的理论是正确的话,我们就可以从生活和治疗的角度出发,又有了以下推论:强壮的人容易死于癌症,所以我们建议,他们不要锻炼身体了,不要增强端粒酶的活性。Fromthiswefurtherbelievethatifthetheorythattelomerasecanrepairchromosomesanddamagetelomeresduetodivisioniscorrect,wecanstartfromthepointofviewoflifeandtreatment,andhavethefollowingcorollary:strongpeoplearepronetodieofcancer.Soweadvisethemnottoexerciseandnottoincreasetheactivityoftelomerase.相反不强壮的人容易死于其它毛病,是因为抵抗力(还是端粒酶的问题)不够,所以必须锻炼身体,以刺激端粒酶的活性。Onthecontrary,peoplewhoarenotstrongaremorelikelytodiefromotherdiseases,becauseresistance(ortelomeraseproblems)isnotenough,sowemustexercisetostimulatetheactivityoftelomerase.对于一般人而言是否要锻炼,一定要掌握好尺度。Fortheaveragepersonwhethertoexercise,mustmasterthescale.而老年人必须要锻炼身体,因为他的体衰是端粒酶不活跃的原因。Olderpeoplemustexercisebecausetheirbodyfailureisthecauseoftheinactivityoftelomerase.90岁以上的老年人,还应该要吃些致癌物质,以增强端粒酶的活性。Peopleover90shouldalsoeatcarcinogenstoboosttelomeraseactivity.他们不用怕癌症,癌症对他们也许并不是坏事。Theydon'thavetobeafraidofcancer.Cancermaynotbeabadthingforthem.有必要说明的是,致癌食品和个体人的关系。Itisimportanttonotethatcarcinogenicfoodshavearelationshipwithindividuals.致癌食品之所以能致癌,就是该物品直接地或间接地刺激了端粒酶的活性。Carcinogenicfoodcancausecancerbecauseitdirectlyorindirectlystimulatestelomeraseactivity.当然,个别人的寿命或生命都是复杂的,我说的是人类寿命的延长一定和实物有关。Ofcourse,thelifespanorlifeofanindividualiscomplicated.Imean,theextensionofhumanlifemusthavesomethingtodowithphysicalobjects.改善了营养结构,一定是或多或少地影响了各个细胞的端粒酶活性,是给整个人类获得长期的影响的积累结果。Improvednutritionalstructure,musthavemoreorlessaffectedthetelomeraseactivityofeachcell,istheaccumulationoflong-termeffectsontheentirehuman.当然个体的,特别的物质对人体的影响也许不需要长期的累积,也许只要几年。Ofcourse,theeffectsofindividual,specificsubstancesonthehumanbodymaynotrequirelong-termaccumulation,perhapsonlyafewyears.有人认为,我们是否可以做实验来获得,食品和端粒酶的活性的关系,理论上可以,但实际上比较困难。Somepeoplethinkthatwhetherwecandoexperimentstoobtaintherelationshipbetweenfoodandtelomeraseactivityistheoreticallypossible,butinpracticeitismoredifficult.因为食品众多而人体细胞的端粒酶也无数,要一一对应起来不容易。Becauseoftheabundanceoffoodandthenumeroustelomeraseofhumancells,itisnoteasytomatchonebyone.所以想通过做实验,以期获得端粒酶活性和食物有关的一般性结论是很难的。Soit'shardtogetageneralconclusionabouttelomeraseactivityandfoodbydoingexperiments.下面谈谈癌症的治疗和预防。Hereisthetreatmentandpreventionofcancer.这里必须再次地强调,如果端粒酶能修补染色体因分裂而损伤的端粒的话,那我们就有治疗癌症的一般性原则,这就是尽量减少端粒酶的活性。Itisimportanttostressagainthatiftelomerasecanrepairtelomeresdamagedbythedivisionofchromosomes,thenwehavethegeneralprincipleofcancertreatment,whichistominimizetheactivityoftelomerase.从这个意义上讲,目前治疗癌症的手段90%都是不当的。Inthissense,90%ofcurrentcancertreatmentsareinappropriate.什么理由,要回答这个问题,需要做如下问题的解答。Forwhatreason,toanswerthisquestion,youneedtoanswerthefollowingquestions.什么是癌症的机制?Whatisthemechanismofcancer?我个人理解就是该细胞对应的端粒酶特别活跃,使得死去的细胞比较少,这就形成了肿瘤。Mypersonalunderstandingisthatthecorrespondingtelomeraseactivityinthecellissoactivethatfewercellsdie,whichcreatesatumor.如果这种肿瘤并不是单纯的,可以蔓延和复制(指别处自然出现)那就是癌症。Ifthetumorisnotsimple,itcanspreadandreplicate(anaturaloccurrenceelsewhere).Itiscancer.所谓癌症转移,并不一定是细胞随血液或其它液体流到它处形成,而多半是其它细胞的端粒酶活性后发或新的刺激形成。Cancermetastasisisnotnecessarilytheformationofcellsflowingintootherplaceswithbloodorotherfluids,butrathertheformationoftelomeraseactivity(Latedevelopment)ornewstimuliinothercells.如果这种猜测没有错的话,我们就可以以此来审视当今的癌症治疗。Ifthisspeculationiscorrect,wecanlookattoday'scancertreatment.人们都说癌症是不治之症,是因为绝大多数有钱人和有权人,已经用了最高科技最好条件都没有治好,所以给人们以这样的经验。Peoplesaycancerisanincurablediseasebecausethevastmajorityoftherichandtherightpeoplehaveusedthebestconditionsofthehighestscienceandtechnologyarenotcured,sogivepeopletheexperience.但是癌症是完全可以改善的,只是方法或观念的问题。Butcancercanbecompletelyimproved.It'sjustamatterofmethodsorideas.这里先说说上海治疗癌症方面的情况。Let'sfirsttalkaboutthetreatmentofcancerinShanghai.过去的上海在治疗癌症方面有两种风格,一种开刀是扩创型的:为了要除去所有的癌细胞,把有怀疑的正常组织都切除。Shanghaiusedtohavetwowaysoftreatingcancer,oneofwhichwasinvasive:togetridofallthecancercells.toremoveallsuspiciousnormaltissue.另一种是简约型的,只对病灶切除。Theotherisaminimalisttype,whichonlyexcisesthelesion.据说这两种风格几年后的病人复发率及死亡率相差不大。Thetwostylesaresaidtohavelittledifferenceinrelapseandmortalityafterafewyears.如果这说法是正确的,那就证明癌症死亡率和复发后的死亡率,和手术治疗的方法无关,应该是有其内应关系存在决定的,现在看来是和癌细胞的端粒酶活性激发有关。Ifthisistrue,itwillprovethatcancermortalityandrecurrentmortalityhavenothingtodowithsurgicaltreatment,butshouldbedeterminedbyaninternalrelationshipthatnowappearstoberelatedtotelomeraseactivationincancercells.目前治疗癌症的方法很多,化疗、放疗、伽马刀、靶向疗法、免疫法、生物治疗、质子刀等,除质子刀外(无数据)效果其实都不理想,和人们的期望值相差甚远,也就是说没有真正能治好癌症。Atpresent,therearemanywaystotreatcancer.Chemotherapy,radiotherapy,gammaknife,targetedtherapy,immunotherapy,biotherapy,protonknife,etc.,withtheexceptionofprotonknife(nodata),theeffectisactuallynotideal,whichisfarfrompeople'sexpectation.Inotherwords,thereisnorealcureforcancer.归纳起来这也是因为癌症治疗没有从本质上着手。insummary,thisisalsobecausecancertreatmentdoesnotstartessentially.那么治疗癌症的本质是什么?Sowhat'sthenatureofcancertreatment?,我认为就是控制癌细胞的端粒酶活性。Ithinkitistocontrolthetelomeraseactivityofcancercells.以上所说的除了能精确的靶向治疗和生物治疗有点不偏外,其它都不恰当。Theaboveisnotappropriateexceptforaccuratetargetedtherapyandbiotherapy.当然话要说回来,现在的治疗方法还是有点效果的,但它只是浮在表面上,解救了当时,即治标不治本:把查得到的肿瘤消除了,减除了肿瘤的现时危险和由此的并发症。Ofcourse,thecurrenttreatmentworksalittlebit,butitjustfloatsonthesurface,rescuingthesymptoms,nottherootcause:removingthetumorfromthesearch,reducingthecurrentriskofthetumoranditscomplications.但内因没有根本改变,甚至起了不好的作用。Buttheinternalcausedidnotchangefundamentally,andevenplayedabadrole.什么不好的作用呢?What'sthebadeffect?就是癌细胞的端粒酶也许更活跃了。Isthatthetelomeraseofcancercellsmaybemoreactive.为了要说明清楚癌症治疗本质,有两个问题需要说明(只是我的看法):一、什么叫健康。Inordertoclarifythenatureofcancertreatment,therearetwoissuesthatneedtobeexplained(justmyopinion:first,whatishealth.健康是指一个人在身体、精神和社会等方面都处于良好的状态。Healthreferstoapersoningoodphysical,mentalandsocialconditions.单单从身体而言,健康是一种动态平衡:均衡地输入和输出能量和物质(甚至允许生长)。Intermsofthebodyalone,healthisadynamicbalance:thebalancedinputandoutputofenergyandmatter(evenallowinggrowth).过分的消耗(大运动)或反过来过分的积累(很少运动)都是不健康的表现。Excessiveconsumption(largeexercise)orconverselyexcessiveaccumulation(littleexercise)isunhealthy.现在有些观点看来也是有问题的,就是想办法增加人体的新陈代谢来提高自己的健康程度。Nowsomeideasseemproblematic,too,tofindwaystoincreaseyourbody'smetabolismtoimproveyourhealth.一是锻炼过头,二是补品泛滥。Oneistoexercisetoomuch,theotheristhefloodingofsupplements.这确实是增加新陈代谢的好方法,但旺盛的新陈代谢一定好吗?It'sreallyagoodwaytoincreaseyourmetabolism,butwillvigorousmetabolismbegood?新陈代谢的旺盛一定是刺激端粒酶活性引起的。Highmetabolismmustbecausedbystimulatingtelomeraseactivity.你当时是很健康的,因为有很多的新细胞支撑着你的人体活性,可潜伏的危险也悄然而至。Youwerehealthyatthattime,becausetherearemanynewcellsthatsupportyourhumanactivity,andthedangerlurks.癌症的可能性增大,或消耗了细胞的分裂次数(假如端粒酶活性不变)。Cancerismorelikely,orconsumesthenumberofcelldivisions(Iftelomeraseactivityisconstant).这两者长期来讲都不好,都不利于长久安康。Botharebadinthelongrunandnotgoodforlong-termwell-being.二、人体的应激反应(stress),也称为狩猎式反应,指机体突然受到强烈有害刺激(如创伤、手术、失血、感染、中毒、缺氧、饥饿等)时,通过下丘脑引起血中促肾上腺皮质激素浓度迅速升高,糖皮质激素大量分泌。Second,thestressresponseofthehumanbody,alsoknownasahuntingreaction,referstoabodysuddenlyexposedtoastrongandharmfulstimulus(suchastrauma,surgery,bloodloss,infection,poisoning,hypoxia,hunger,etc.)Thehypothalamuscausesarapidincreaseintheconcentrationofcorticotropichormoneinthebloodandalargeamountofglucocorticoidsecretion.通常是机体的统一反应,因此认为具有适应性的意义。Itisgenerallyauniformreactionoftheorganismandisthereforeconsideredtobeofanadaptivesignificance.这里描述的是表面现象,真正的人体应激反应,我认为应该是人体的快速自身修复——即增加了相应器官或组织的代偿能力。Whatisdescribedhereisasurfacephenomenon,arealhumanstressreaction,andIthinkitshouldbethefastself-healingofthehumanbody_thatis,increasesthecompensatoryabilityofthecorrespondingorgansortissues.那么凭什么呢?Sowhatdoesitdependon?自然我也认为是人体的特殊功能(不知道什么原因)刺激了端粒酶的活性,使得新细胞的大量产生。Naturally,Ialsothinkthatthespecialfunctionofthehumanbody(forsomereason)stimulatestheactivityoftelomeraseandmakesnewcellsproduceinlargequantities.有了以上两个问题的说明和指导,我们再次审视当下的癌症康复治疗。Withthesetwoquestionsexplainedandguided,were-examinethecurrenttreatmentofcancerrehabilitation.在治疗后到复发前的这段时间内,癌症病人通常被认为是康复了。cancerpatientsaregenerallyconsideredtohaverecoveredduringtheperiodbetweentreatmentandrelapse.因为人体的应激反应使得开刀失去的组织很快修复,恢复了功能。Becauseofthestressresponseofthehumanbody,thetissuethatwaslostintheoperationwasrepairedquickly.,andthefunctionisrestored.人体各器官能和往常一样正常运行。Theorgansofthehumanbodycanfunctionasusual.加上病人们都要进行病后调理,或者少量运动或者吃相应的补品和其它方法以增强自己的体质。Pluspatientsneedtotakecareofthemselves,ortakesmallamountsofexerciseortakeappropriatesupplementsandothermethodstoimprovetheirhealth.我们现在都认为这是最有效的后续保养,其实不然。Wenowallthinkthisisthemosteffectivefollow-upmaintenance,butitisnot.因为这些前提都是要增加端粒酶的活性,我相信人体的各个细胞的端粒酶是有关联的(不知道关联的程度)。Becausethesepresuppositionsaretoincreasetheactivityoftelomerase,Ibelievethatthetelomeraseofhumancellsisrelated(Idonotknowtheextentoftheassociation).刺激了其它端粒酶的活性,必然或多或少地影响了癌细胞的端粒酶,这就是为癌症的所谓转移复发奠定了基础。Itstimulatestheactivityofothertelomerase,andinevitablyaffectsthetelomeraseofcancercellsmoreorless,whichlaysthefoundationfortheso-calledmetastasisandrecurrenceofcancer.所以我的结论是,一切有损于组织或器官的治疗癌症的方法都不是好方法。Somyconclusionisthatanycancertreatmentthatharmstissuesororgansisnotagoodway.这就告诉我们癌症是难于治愈的,或者就是无效的(不指个别人,有些人能自愈)。Thistellsusthatcancerisdifficulttocure,orineffective(notindividuals,somepeoplecanhealthemselves).下面谈谈我对治疗癌症的基本想法。Here'smybasicideaofcancertreatment.先对目前治疗癌症作一个基本评价。Makeabasicevaluationofthecurrenttreatmentofcancer.应该说没有什么效果。Itshouldbesaidthatthereislittleeffect.有人会说,有些人康复了,有些人延长了寿命(由5年、8年的成活率增加看出)。Somepeoplewillsaythatsomepeoplehaverecovered,somepeoplelivelonger(asshownbythe5-year,8-yearincreaseinsurvivalrates).这些看起来好像是治疗的效果,但,其实不然,有两个原因来说明:第一、每个人的身体状况不一样,有些肿瘤是会慢慢退缩的,也就是自愈。Thesemayseemliketherapeuticeffects,buttherearetworeasonswhy:First,everyone'sphysicalconditionisdifferent,sometumorswillslowlyretreat,thatis,self-healing.我们很多人都有体会,去年查身体发现了小肿块,没有管它两三年后再查,发现没有了。Manyofushavetheexperience,lastyearthebodyfoundasmalllump,regardlessofittwoorthreeyearslater,foundno.癌症也会有这样的情况发生。Cancercanhappeninthesameway.我的朋友和他的父母亲都有较严重的痔疮,30年每年都发作数几十次也没有管它(不治疗),在59岁以后,他们的痔疮都基本好了(自愈)。Myfriendandhisparentsbothhaveseverehemorrhoidsandhavehaddozensofepisodesayearfor30years.Don'tcareaboutit.Aftertheageof59,theirhemorrhoidswerebasicallywell.还有治好的“癌症”多半是误诊,也就是肿块本来就不是癌症(过去民谚说:“十个癌症九个埋,还有一个不是癌”),只是样子像癌症,可能各类指标和切片是癌症的特征,或者是炎症(像肺的毛玻璃样多半是),碰到一个不良的医生(医疗水平差或医道底下)会按照癌症来治疗,自然是“治好”了。Therearealso"cancers"thatareoftenmisdiagnosed,thatis,lumpsarenotcanceratall.(astheoldsayinggoes,ofthe10cancerpatients,"ninecancersareburied,andoneisnotcancer.")theyjustlooklikecancer,andmaybeallkindsofindicatorsandslicesarethecharacteristicsofcancer.Orinflammation(muchliketheglassinthelungs),whenitcomestoabaddoctor(poormedicaltreatmentordoctors'lowmoralstandards),willbetreatedbycancer,andnaturallyitwillbecured.还有原位癌有不少是能自愈的(我的意思,是癌还是要早治疗的),特别是甲状腺乳腺以及前列腺和鼻窦的原位癌自愈的比较多。Therearealsomanyinsitucancersthatareself-healing(Imean,cancerisstilltobetreatedearly),especiallyinthethyroidglandandintheprostateandsinuses.极其少的转移癌也能自愈。Veryfewmetastaticcancerscanalsohealthemselves.第二、5年、8年的成活率增加其实是假象,过去发现的癌症多半是中期或晚期的,成活5年以上已经是很少见的了。Second,theincreaseinthesurvivalrateoffiveyearsandeightyearsisanillusion.Mostofthecancersdiscoveredinthepastareintermediateoradvanced,anditisveryraretosurviveformorethanfiveyears.但现在由于医学检查手段的先进,大多数癌症被早期或更早期发现了,这些人十年生存都不稀奇。Butnowthatmostcancersarediscoveredearlyorearlierthankstoadvancedmedicaltechniques,itisnotunusualforthesepeopletosurviveforadecade.因为癌症是慢性病,不治疗的癌症患者从他身上第一个癌细胞的出现起到其死亡,大约要16—18年。Becausecancerisachronicdisease,untreatedcancerpatientsfromtheappearanceofthefirstcancercelltotheirdeathtakeabout16-18years.过去癌症被发现应该是12年后的情况,而现在大约是6年的情况(超级ct检查),所以多存活了6年是很正常的,更何况癌症病人是大多死于并发症,现在医疗水平有很大的进步,控制并发症的能力大为提高。(我认为癌症病人看病就是为这个),这个也为癌症病人的存活提供了两年左右的帮助。当然也有被癌症吓死的,早发现可能被早吓到,这个对延长存活是适得其反的。Inthepast,cancershouldhavebeendiscovered12yearslater,butnowitisabout6years(supercttest),soitisnormaltosurviveforanothersixyears.Besides,mostcancerpatientsdiefromcomplications,andnowmedicalstandardshaveimprovedgreatly.Theabilitytocontrolcomplicationshasbeengreatlyimproved(IthinIthinkthat'swhatcancerpatientsdo).Thishasalsohelpedcancerpatientssurviveforabouttwoyears.ofcourse,therearethosewhoarescaredtodeathbycancer,andthosewhofinditearlymaybescared.Thisiscounterproductivetoprolongingsurvival.所以我的结论是,目前治疗的效果不是医生们说的那么大。Somyconclusionisthatthecurrenttreatmentisnotaseffectiveasdoctorssay.关于治疗和预防问题。Ontreatmentandprevention基本原则是考虑到康复过程时,尽量不要增加(或略微增加)端粒酶的活跃,因为无论什么治疗都要损坏健康的细胞,自身的正常细胞应激修复(指代偿能力)本质就是靠刺激了端粒酶活跃的结果,而端粒酶的活跃会进一步引发新一轮癌症的发生(以转移为特征),所以不要因为治疗旧的癌症而引发新的癌症,这是最重要的原则。Thebasicprincipleistotrynottoincrease(orincreaseslightly)theactivityoftelomerasewhentakingintoaccounttheprocessofrehabilitation,becauseanytreatmentwilldamagehealthycells,Thenatureoftheirnormalcellularstressrepair(compensatoryability)istheresultofstimulatingtelomeraseactivity.Telomeraseactivitycanfurthertriggeranewroundofcancer(characterizedbymetastasis),soitisthemostimportantprinciplenottocausenewcancerbytreatingoldcancers.身体的正常细胞应激修复最强的器官是舌头,其次是肝脏。这里的开刀要特别注意,因为它们复制细胞能力强,是端粒酶活跃(被应激)产生的结果。Thestrongestorganofnormalcellstressrepairinthebodyisthetongue,followedbytheliver.Thesurgeryhererequiresspecialattention,astheyarehighlyreplicatingcellsandaretheresultofactivetelomeraseactivity(stress).我相信癌症的端粒酶也会被应激而活跃,可能会有最不好的结果——癌症广泛转移。Ibelievethatthetelomeraseofcancerisalsoactivatedbystress,possiblytheworstresult-widespreadmetastasisofcancer.所以肝癌开刀要谨慎(肝癌要不要开刀,这个问题是要要仔细琢磨)。Therefore,thequestionofwhetherthelivercancershouldbeoperatedonistobecarefullyconsidered相反的是,代偿能力弱的前列腺是很合适开刀治疗的。Onthecontrary,theprostatewithweakcompensatorycapacityissuitableforsurgicaltreatment.纵观几十年的癌症治疗,大面积创伤性的治疗方法一定是不好的。Throughoutdecadesofcancertreatment,large-scaletraumatictreatmentmustbebad.过去肺癌开刀是大面积创伤性的治疗方法,没有看到好的结果。inthepast,surgeryforlungcancerwasalarge-areatraumatictreatment,butnogoodresultswereseen.现在普遍是微创(单孔或双孔)是很好的,必要的话最好是单叶全部切除,因为这个单叶不会再长了,肺的端粒酶不会过分活跃,转移的概率就小。Minimallyinvasive(singleordoublehole)isnowagoodidea.Ifnecessary,itisbesttoremovethesinglelobecompletely,becausethesinglelobewillnotgrowanylonger,thelungtelomerasewillnotbetooactive,andtheprobabilityofmetastasiswillbesmall.相反的是部分切除的话,它还会生长,转移的概率就大。Onthecontrary,ifitispartiallyresected,itwillgrow,andtheprobabilityofmetastasiswillbehigh.这个思维和一般人不一样。Thisthoughtisdifferentfromtheaverageperson.开刀后一般都要化疗,说是要阻碍癌细胞的转移,这个观点对不对?Afteroperationcommonlywantschemotherapy,sayiswanttoblockthemetastasisofcancercell,thisviewisright?我认为不对。Idon'tthinkso.因为不分青红皂白的杀死所有的细胞,虽然对于暂时遏制癌症的发展有一定的作用。Becauseindiscriminatelykillingallthecells,althoughforthetimebeingtocurbthedevelopmentofcancer.但是为了恢复健康各个器官或细胞的代偿做用,会告诉我们端粒酶更活跃了,癌细胞的活力更强大,没有过多少时间,转移就发生了。Buttorestorethecompensatoryuseofvariousorgansorcells,ittellsusthattelomeraseactivityismoreactive,cancercellsaremoreactive,andmetastasesoccurwithinashortperiodoftime.所以不提倡,大强度化疗,要适可而止。Thereforedoesnotadvocate,thebigintensitychemotherapy,mustbeabletostop.有人说,不彻底的化疗是癌症复发的原因。Somepeoplesaythatincompletechemotherapyisthecauseofcancerrecurrence.他们以为是原位癌的细胞随血液流动引起的转移,要杀死这些癌细胞就必须要彻底的化疗。Theythoughtitwascancercellsinsituthatweremetastasizedbybloodflow,tokillthesecancercells,wemusthavethoroughchemotherapy.殊不知癌细胞的抗药性可能很强大,根本不能完全杀死它(可能人已经被杀死了,它还没有死)。However,itisnotknownthattheresistanceofcancercellscanbesostrongthatitcannotbecompletelykilled(maybepeoplehavebeenkilled,itisnotdeadyet.)然而还有更重要的问题,即使全部杀死了这些细胞,那么由于机体恢复引起的癌症的端粒酶活跃,使得新原位癌又产生了(两年左右),这才是真正的复发,这才是目前所谓癌症转移的本质。Butthereisamoreimportantproblem,evenifallofthesecellsarekilled,andthetelomeraseactivityofthecancerthatiscausedbytherecoveryofthebodycausesanewcancerinsitu.(abouttwoyearsago),thisistherealrelapse.Thisistheessenceofwhatisnowcalledcancermetastasis.(其实,癌症病人本身就是发生癌症的敏感体,新癌发生的概率极大,所以不要刺激端粒酶活跃。)Infact,cancerpatientsthemselvesarecancer-sensitive,theprobabilityofnewcancerishigh,sodonotstimulatetelomeraseactivity.至于靶向治疗、伽马刀和质子刀,只要精准那是最好的了,因为对身体的损伤可以最小,端粒酶的刺激也最小,复发转移的可能性也最小。Asfortargetedtherapy,thegammaknifeandprotonknife,aslongasprecisionisthebest,becauseoftheminimaldamagetothebody,theminimumstimulationoftelomerase,andtheleastpossibilityofrecurrence.但是前两者很难做到精准。Butthefirsttwoaredifficulttobeaccurate.靶向治疗理论上很完美,药物只杀死癌细胞。Targetedtherapyisperfectintheory.Drugskillonlycancercells.可各人对药物的敏感程度是不一样的。thedegreeofsensitivityoftheindividualtothedrugisdifferent.也许同一种癌细胞各种人的具体细节是不一样的,这样药物的精准度是大打折扣的。Perhapsthedetailsofthesamecancervaryfrompersontoperson,sotheaccuracyofthedrugiscompromised.伽马刀相当于极微创手术,辐射对人体的伤害有一点,但不会因此产生新癌症。Gammaknifeisequivalenttominimallyinvasivesurgery,radiationdamagetothehumanbodyalittle,butwillnotcausenewcancer.但还是精准度的问题。那些是癌非癌的细胞(未完全癌化的细胞)可能被漏网。计算机模拟的图不一定准确,精准操作难度大。Butit'sstillamatterofaccuracy.Thosecellsthatarenotcompletelycancerizedmaybefunneled.Computersimulationofthemapisnotnecessarilyaccurate,accurateoperationisdifficult.质子刀比它更好一点。Theprotonknifeisbetterthanit.但是不管怎么样的开刀,器官的缺损部位要修复,都可能是复发转移的原因。However,nomatterhowtheoperation,thedefectoftheorgantorepair,maybethecauseofrecurrenceandmetastasis.癌症的难治就是这个道理。Thisiswhatcancerishardtocure.只是小创伤复发转移概率小而已。Onlysmalltraumarecurrenceshavelittleprobabilityofmetastasis.由此我们想到预防问题。Fromthiswethinkoftheproblemofprevention.有两个预防问题,一个是预防癌症发生,另一个是预防癌症复发。Therearetwopreventionproblems.Oneispreventionofcancerandtheotherispreventionofcancerrecurrence.预防的原则和治疗的原则是一样的:尽量不要让端粒酶多活跃。Theprincipleofpreventionisthesameasthatoftreatment:trynottomaketelomerasemoreactive.由人体寿命和端粒酶活跃的曲线的后半段可以看出,生命长寿和生命活力可能反相关的。Fromthesecondhalfofthecurveoflifespanandtelomeraseactivity,itcanbeseenthatlongevityandvitalitymaybeinverselycorrelated.生命活力强的人,也即新陈代谢旺盛的人,寿命可能并不长。Energeticpeople,thatis,peoplewithhighmetabolism,maynotlivelong.他们多半死于癌症而非心血管毛病;而生命活力弱的人,虽然他们表现的病病恹恹,寿命一般比身体强壮的人长。Mostofthemdiefromcancerratherthanfromcardiovasculardisease;andpeoplewhoareweakinlife,thoughtheyaresickly,tendtolivelongerthanpeoplewithstrongbodies.他们多半死于心血管毛病,而癌症的得病概率比较低。Theyaremorelikelytodiefromcardiovascularproblems,whilecancerislesslikely.当然癌症发生是几个原因共同作用:遗传、环境和饮食等。Ofcourse,cancerhappensforseveralreasons:heredity,environmentanddiet.主因是遗传,而环境不好和进食不佳是加快了遗传的反生、质变和突变。Themaincauseisheredity,whilepoorenvironmentandpooreatingspeedupgeneticreactions,qualitativechanges,andmutations.预防的要点在哪里,就在端粒酶上。Thepointofpreventionliesintelomerase.对于癌症发生:身体强壮的人和有癌症家族史的人群要少锻炼身体,“以静制动”。Forcancer:strongpeopleandpeoplewithafamilyhistoryofcancershouldexerciseless.中国古代有个名人叫诸葛亮,他有句养生名言,叫“静以修身,俭以养德”,就有这个含义。InancientChina,therewasafamousmannamedZhugeLiang.Hehadafamoussaying,"quietwithself-cultivation,thriftwithvirtue",that'swhatitmeans...虽然他不知道癌症,但他懂人生修养的。Althoughhedoesn'tknowcancer,heknowslifewell.虽然他死的不晚,那是他劳累所致。Althoughitwasnottoolateforhimtodie,itwasbecauseofhistiredness.还有龟能长寿的原因也许就是这个道理。Andperhapsthereasonwhyturtleslivelonglivesisprobablythereason.吃的方面,中医的“引发食物”要少吃。Intermsoffood,the"Triggerfood"oftraditionalChinesemedicine(TCM)shouleeatless.这些发物可能对应于端粒酶的活性。Theseproductsmaycorrespondtotelomeraseactivity.还有,身体尽量不要受伤,所有受伤,身体都要修复的,都要增加端粒酶的活性。Also,thebodyshouldtrynottobehurt,allinjuries,thebodytorepair,toincreasetheactivityoftelomerase.修复的越快,癌症的发生可能越大,这也是预知癌症发生的一般标准。Thefastertherepair,thegreaterthelikelihoodofcancer,whichisthegeneralstandardforpredictingcancer.特别要强调的是,怀孕的妇女,如果你平时很少有感冒之类的小毛病,或有明显的家族史的,不要剖腹产了,否则会增加发生癌症的概率。Inparticular,pregnantwomen,ifyourarelyhaveacold,orhaveanobviousfamilyhistory,donothaveacaesareansection,otherwisewillincreasetheprobabilityofcancer.对于癌症复发:原则上和上相同。Forcancerrecurrence:inprinciplethesameasabove.但是要注意机体的康复和新癌产生的关系把握,这难度很高。Buttopayattentiontotherecoveryofthebodyandtherelationshipbetweennewcancergrasp,thisisverydifficult.一方面身体要恢复,是靠端粒酶的活性。Ontheonehand,therecoveryofthebodydependsontheactivityoftelomerase.进补营养和锻炼身体都能起到这个作用,这也是必须的。Nourishmentandexercisecanbothplaythisrole,whichisalsonecessary.另一方面,癌细胞也被逐渐恢复了,并且新增了其它的癌细胞。Ontheotherhand,cancercellshavebeengraduallyrestoredandothercancercellshavebeenadded.恢复身体到什么程度对生命最有益看来是个的严重的问题,我们怎么把握呢?Howcanwegrasptheseriousproblemofrestoringthebodytowhatextentitismostbeneficialtolife?看来还要再实践,理论说不清,因为癌症发病机制我们不清楚。It'seemsthatwestillhavetopractice,theoryisnotclear,becausewearenotclearaboutthemechanismofcancer.就目前而言,我们锻炼身体的目的,主要是恢复抵抗力以抗拒细菌和病毒以及衣原体、病原体的侵害。Fornow,themainpurposeofourexerciseistorestoreresistancetobacteriaandvirusesandchlamydiaandpathogens.如果你的体力已经达到能抗拒这些毛病了,就没有必要多营养和锻炼了。Ifyouarephysicallystrongenoughtoresisttheseproblems,thereisnoneedformorenutritionandexercise.举个例子,中医癌症康复治疗多用泡澡。Forexample,traditionalChinesemedicineforcancerrehabilitationisoftenusedinbaths.(Takealongbath.)医理是活血,以增强人体的抵抗力。principlesofmedicalscienceistopromotebloodcirculationinordertoenhancethebody'sresistance.这对于人体机理恢复有很大的作用,它可以阻止因为开刀损害身体而引起的其它毛病。Thishasagreateffectontherecoveryofhumanmechanism,itcanpreventotherproblemscausedbysurgerydamagethebody.但不要长久,身体基本恢复就可以了(恢复到70%)。Butdon'tlastlong,yourbodywillbasicallyrecover.(Backto70%).以上是我对癌症和癌症治疗和预防的一些不成熟的看法,希望对医患双方都有点帮助,这是我的心愿。Thesearesomeofmyimmatureviewsoncancerandcancertreatmentandprevention,hopingtohelpbothdoctorsandpatients.Thisismywish.我个人始终认为,对于癌症的治疗,主要是治疗它的并发症,并非治疗癌症本身。Personally,Ihavealwaysbelievedthatcanceristreatedprimarilyforitscomplications,notforcanceritself.

    丧尸舞2021-01-08

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    俗话说,一种米养百种人,林子大了什么鸟都有。我们与社会接触,知道有好人、坏人,老实人、奸诈人,还有好好先生、差不多先生和“你就是”先生。今天就说说“你就是”先生。什么叫“你就是”先生呢?子曰:舍曰欲之而必为之辞。我们知道,有种人他想要什么或表达什么不直说,而是通过委婉的方式来表达诉求——有时是拉不下面子,有时是故作矜持,有时则是不屑。我们知道,有种人喜欢给人起绰号,给人贴标签,别人反过来这么对待他时,他就会激动得想要打架。我们知道,有种人喜欢以自己的认识论去厘定一个人,不接受辩驳,也不接受自己的局限,认定了就一口咬定到底。争辩不过时,就大吼冷场以为胜利,或冷战以拖延为胜利。话休饶舌,言归正传。昔者余游于蜀地,遇一人焉,多智而狡,与之言侃侃似有道理,揣摩之则一孔之见。等闲人不识其真伪,多以为高见。其亦常自以为木铎。一日,吾掩卷思忖,其人忽至,见而问之曰:“何事苦思若此?何不与言?”答曰:“思道之动也。夫道者,其静也如水,其动也如返。迎之不见其首,随之不见其后,绳绳兮不可名,惟恍惟惚,其中有象,其中有真。”其人挥手噘嘴摇头而曰:“尔之言形而上,皆为虚妄,请听我言。世间万物,无非物理,物理所不能及,便是不存在,便是虚妄。”余闻之瞠目结舌,曰:“夫高下相倾,长短相随,音声相和,良有以也。道法自然,虚实相生,形而下者谓之器,形而上者谓之道,何虚妄之有?且夫道之动也,其反也。一生二,二生三,三生万物无有已时,此目见而耳闻,焉得为虚妄?夫为学者于其所不知也,盖阙如也。六合之外,圣人尤且存而不论,况于吾辈乎!”其不屑曰:“世无圣人,亦人焉而已矣。且看计算机语言,零一而已。两相组合,而为板凳,而为桌椅,而为食物,而为天地……无有已时,此便是极道。以此不能涵盖推理者,则为虚妄。观世界文明,莫有出于此者,尔之道,小道尔,虚妄而不切实际。”余笑而言曰:“君之所言,实道之分支类阴阳、二气论也,然又在下矣。以物逆推道之本源,犹攀枝叶而求其木,焉能得全?”“此已极矣,尔能觅其不能衍化之物乎?不能则是极道!且尔焉知虚者不为实?实者不为虚?焉知现实非虚幻,而虚幻非现实?”余恬然笑曰:“请循其本。道无,为天地之始;道有,为万物之母。夫以有推无,可乎?有无相生,非大智博识者不能为也!请循其本,道之有也为一,三生万物也循道。为天地、为树木,为山石,为水冰……每下而愈况。逆而求之,有之在物理之内,无之莫非物理之外乎?”其不耐曰:“此亦不切实际,实不存在。若我不能触摸感应者,尔不能具象而实证者,皆为虚。”余哑然失笑,默而不语。又一日,吾笔耕,为《蝶梦仙经》,其踱来见之,曰:“吾然之矣,尔欲为《红楼梦》。”余无言以对。止诗文点缀文章而已,焉能为《红楼梦》?古之书皆然。又一日,坐于中庭,三两友人与之偕来论道。照前言辨良久,各执一词不能下,必要实证之而后能服。举日月四时天经地义以对,曰不然;举生老病死以对,又曰不然;举五行生克转化以对,亦曰不然。余曰:“道之所观,譬诸树也。远而观之,幢幢如盖,只见叶子不见躯干。迫而察之,方得全貌。”又曰:“以叶求树,可得全树乎?斯不亦以物求道之实耶?夫为道者不欲杂,杂则多,多则扰,扰则忧,忧则不救。人之为道,其出越远,其知越少。非知之少也,离道远尔。是以见素抱朴,守一不离。”其莫知吾言,依旧重新执其言而辨。我对曰:“方才已言明,尔等不能明我之言。”彼曰:“我等为高学历者,焉能听不懂尔之言?尔未能言明,勿要狡辩。”夫子曰,中人以上,可以语上也;中人以下,不可以语上也。余于是乃止,其人沾沾自喜,以为胜也。又一日,相坐闲谈,其言曰:“我观尔似某某人,口曰不要,手已伸出,沽名钓誉而已。”吾纳闷之,不知言之何起,一时无言。闻于旁人,则皆言我有仙气,清心寡欲不类人间浑浊者。其不信人有能禁人欲抱道者,故诘难之。余闻之也哑然失笑。我何曾言于人?吾亦何曾禁欲抱道,皆尔等自言自语。我坐于中庭,则遭无妄之灾。又一日,余友荐《欢乐英雄》与我,观其书有王动者,我赞叹曰正类斯人!余友曰,然而,正如其人!友闲坐与之言,其色大变,如斗鸡之相对,正色对余曰:“尔不能言我,不要言我,勿要背后与人言我。”如此再三,慎重之至,如临大敌。余见而怪之,忽忆子之言:己所不欲,勿施于人。又一日,众朋欢聚,论及人伦大道,其曰:“人性以外,皆是虚伪。尤其孔子,最反人类。”吾闻而怪之,与之言乃董仲舒及宋明儒者曲解所致,其不信。与之书观,则如遇蛇蝎,连连挥手曰:“皆是封建糟粕,无需看亦不必看。众人皆言之,焉能有错!”余闻之怅然,不久离蜀远游,后归深圳。

    武陵年少时2020-12-29

  • 吞噬星空之武祖传说快眼

    最新章节: 一剑杀
    在全面深入铺开脱贫攻坚之,党建引领、示范、带动工尤为重要,如何更好地发挥建工作在脱贫攻坚中的作用探索新的模式,为脱贫攻坚作注入“强心剂”,更好地赢脱贫攻坚战。强化顶层驱。坚持调研先行,强化挂图战,科学确定扶贫工作的目任务,精准施策,深度扶贫科学配置资源。各级在脱贫坚综合要求的基础上,强化系行业实际,找准扶贫着力,聚焦主攻目标。强化梯次进。扶贫工作坚持由急到缓梯次推进,让群众在得到实中感受党的温暖,坚定脱贫坚的信心和决心。在纵向上按照“惠民优先、发展持续的原则,强化项目带动,科把控扶贫节奏。强化共建联。党员“一对一”结对帮扶广泛宣传扶贫工作。将拔除根、思想脱贫作为关键,强基层党组织共建,增强软实,坚持扶志扶智并举,广泛传动员,形成联动格局,坚打赢脱贫攻坚战

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  • 乱入韩娱无弹窗广告

    最新章节: 往事
    巴金说:“一个美国人敢站出来说真话,因为他知道身后会有千万个美国人用行动支持他。一个中国人不敢站出来说真话,因为他知道周围的同胞会默默地与他保持距离。”

    葱不吃糖2021-01-10

  • 网游之屠龙巫师

    最新章节: 海护王大有深意
    秋风清,秋月明,落聚还散,寒鸦栖复惊相思相见知何日,此此夜难为情。赏析 此诗写在深秋的夜晚诗人望见了高悬天空明月,和栖息在已经完叶子的树上的寒鸦也许在此时诗人正在念一个旧时的恋人,情此景,不禁让诗人伤和无奈。这是典型悲秋之作,秋风、秋、落叶、寒鸦烘托出凉的氛围加上诗人的丽的想象,和对自己心的完美刻画让整首显的凄婉动人。  诗的体式许多人认为像一首小词,具有明的音乐特性。赵翼的陔余丛考》卷二十三:“三五七言诗起于太白:‘秋风清,秋明。……’此其滥觞。刘长卿《送陆澧》云:‘新安路,人来。早潮复晚潮,明日知何处?潮水无情亦解,自怜长在新安住。宋寇莱公《江南春》云:‘波渺渺,柳依。孤林芳草远,斜日花飞。江南春尽离肠,苹满汀洲人未归。……”指出了它和“南春”词牌的渊源关。南宋邓深曾依此调填写词作,名为“秋清”。清人还把李白首诗当作是一首创调而收入《钦定词谱》云:“本三五七言诗后人采入词中。” 此诗只题作“三五七”而不言及诗歌内容题,可知诗人的创作图本是偏重作品的形特征,即只要满足全两句三言、两句五言两句七言的体式要求能成诗了。可以说,题中已经包含了明确诗体形式内涵。严羽《沧浪诗话》中的“体”一章就说道:“三五七言。”自注云“自三言而终以七言隋世郑世翼有此诗:秋风清,秋月明。落聚还散,寒鸦栖复惊相思相见知何日,此此夜难为情。’”郭虞先生校释曰:“沧所谓郑世翼有三五七,不知何据。案《诗玉屑》无‘秋风清’下各句,以从《玉屑为是。‘秋风清’云,见《李太白集》,当是李作。”  但李这首诗也不能算是创之作,因为初唐时僧义净作有一首《在西怀王舍城》,此诗因体式特征而名为《一五七九言》。李白的三五七言》只是《一五七九言》的变体,去起首的“一言”和尾的“九言”,即为三五七言”。王昆吾《唐代酒令艺术》中证义净诗为“唱和之”。李白这首《三五言》可能也是他与其诗人的“唱和诗”。三五七言”是对所酬诗歌格式的限制,这一个“总题”,众人具体创作时可根据所内容再命一个相应的题。  此诗即使不创体之作,也是李白终确立了“三三五五七”格式作为一种独的曲辞格甚至成为一时兴诗体的地位。这仅是因为他借鉴和总了许多人应用三五七句式的经验,更得力他自身歌辞创作中灵运用此类格式的实践悟,因而他的《三五言》能表现出“哀音节,凄若繁弦”(《宋诗醇》卷八)的艺魅力

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